![]() The indigenous people of Llanos (Venezuela), chewed the bark of caapi instead of brewing it as a drink. Īlthough utilised among the indigenous tribes of South America for hundreds and perhaps even thousands of years, caapi was not identified by westerners until 1851, when Richard Spruce, an English botanist, described it as a new species. History įirst mention of caapi comes from early Spanish and Portuguese explorers and missionaries who visited South America in the 16th century, describing ayahuasca brews as “diabolic” and dangerous decoctions. In vivo studies conducted on the dentate gyrus of the hippocampus noted an increase in the proliferation of BrdU positive cells in response to 100 μg of 5-MeO-DMT injected intravenously in the adult mouse brain. More specifically, in vitro studies showed that harmine, tetrahydroharmine and harmaline, stimulated neural stem cell proliferation, migration, and differentiation into adult neurons. Several studies have shown the alkaloids in the B. See also: Ayahuasca § Neurogenesis N,N-dimethyltryptamine § Neurogenesis and psychoplastogen In addition to beta-carbolines, caapi is known to contain proanthocyanidins, epicatechin and procyanidin B2, which have antioxidant properties. Īlkaloids are present in all parts of the plant. The stems contain 0.11–0.83% beta-carbolines, with harmine and tetrahydroharmine as the major components. The MAOIs allow the primary psychoactive compound, DMT, which is introduced from the other common ingredient in ayahuasca Psychotria viridis, to be orally active. These alkaloids of the beta-carboline class act as monoamine oxidase inhibitor (MAOIs). Phytochemicals Alkaloids Ĭaapi contains the following harmala alkaloids: The vine can grow up to 30 m (98 ft) in length, twining on other plants for support. It resembles Banisteriopsis membranifolia and Banisteriopsis muricata, both of which are related to caapi. Description Ĭaapi is a giant vine with characteristic 12–14 mm (0.5–0.6 in) white or pale pink flowers which most commonly appear in January, but are known to bloom infrequently. Other names include Banisteria quitensis, Banisteriopsis inebrians, and Banisteriopsis quitensis. ![]() ![]() An earlier name for the genus was Banisteria and the plant is sometimes referred to as Banisteria caapi. It is commonly used as an ingredient of ayahuasca, a decoction with a long history of its entheogenic (connecting to spirit) use and its status as a "plant teacher" among the Indigenous peoples of the Amazon rainforest.Īccording to The CRC World Dictionary of Plant Names by Umberto Quattrocchi, the naming of the genus Banisteriopsis was dedicated to John Banister, a 17th-century English clergyman and naturalist. Banisteriopsis quitensis (Nied.) Mortonīanisteriopsis caapi, also known as, caapi, soul vine, or yagé ( yage), is a South American liana of the family Malpighiaceae.Banisteria inebrians (C.V.Morton) J.F.Macbr. ![]()
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